si:ch211-247j9.1 si:ch211-247j9.1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: si:ch211-247j9.1provided by ZNC
Official Full Name: si:ch211-247j9.1provided by ZNC
Primary source: ZFIN:ZDB-GENE-091204-212
See related: Ensembl:ENSDARG00000079283 AllianceGenome:ZFIN:ZDB-GENE-091204-212
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including activation of GTPase activity; negative regulation of Rac protein signal transduction; and negative regulation of ruffle assembly. Predicted to act upstream of or within signal transduction. Predicted to be active in focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 21

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (32318187..32345973)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (32284921..32312707)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTPase activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in activation of GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell development	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of Rac protein signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of ruffle assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info
involved_in system development	IEA Inferred from Electronic Annotation more info
involved_in wound healing, spreading of epidermal cells	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in focal adhesion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: rho GTPase-activating protein 24-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007132.7 Reference GRCz11 Primary Assembly

Range

32318187..32345973

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017352979.2 → XP_017208468.1 rho GTPase-activating protein 24-like isoform X2

UniProtKB/TrEMBL

A0A8M6YUQ8
XM_005161401.4 → XP_005161458.1 rho GTPase-activating protein 24-like isoform X1

UniProtKB/TrEMBL

A0A8M2B8C7

Related

ENSDARP00000128607.3, ENSDART00000154105.3

Conserved Domains (1) summary

cl02570
Location:57 → 255

RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
XM_693448.8 → XP_698540.4 rho GTPase-activating protein 24-like isoform X4

UniProtKB/TrEMBL

A0A8N7T6W7, E9QDL0

Related

ENSDARP00000102953.3, ENSDART00000110137.5

Conserved Domains (1) summary

cl02570
Location:33 → 229

RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
XM_005161403.4 → XP_005161460.1 rho GTPase-activating protein 24-like isoform X3

UniProtKB/TrEMBL

A0A0R4IDX6, A0A8M2B8G0

Related

ENSDARP00000132315.2, ENSDART00000161723.2

Conserved Domains (1) summary

cl02570
Location:33 → 230

RhoGAP; RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...